鲜竹沥正丁醇部位的化学成分研究

林凯鹏, 付辉政, 周志强, 姚金龙, 赵青群, 罗跃华

中国药学杂志 ›› 2020, Vol. 55 ›› Issue (16) : 1325-1330.

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中国药学杂志 ›› 2020, Vol. 55 ›› Issue (16) : 1325-1330. DOI: 10.11669/cpj.2020.16.002
论著

鲜竹沥正丁醇部位的化学成分研究

  • 林凯鹏1,2, 付辉政2*, 周志强2, 姚金龙2, 赵青群2, 罗跃华2*
作者信息 +

N-Butanol-Soluble Chemical Constituents from Bamboo Juice

  • LIN Kai-peng1,2, FU Hui-zheng2*, ZHOU Zhi-qiang2, YAO Jin-long2, ZHAO Qing-qun2, LUO Yue-hua2*
Author information +
文章历史 +

摘要

目的 研究鲜竹沥正丁醇部位的化学成分。方法 通过硅胶柱色谱、ODS柱色谱、大孔树脂柱色谱、液相色谱等方法进行分离纯化,根据波谱数据分析和相关资料鉴定化合物的结构。结果 从鲜竹沥正丁醇部位分离得到15个化合物,分别鉴定为:(+)-南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷(1),5,5'-二甲氧基落叶松树脂醇-4'-O-β-D-吡喃葡萄糖苷(2),丁香脂素4'-O-β-D-葡萄糖苷(3),(-)-4-epi-南烛木树脂酚(4),(-)-南烛木树脂酚-2α-O-β-D-吡喃葡萄糖苷(5),(+)-南烛木树脂酚(6),8, 8'-bisdihydrosiringenin glucoside (7),2,4,6-三甲氧基苯酚1-β-D-葡萄糖苷(8),threo-8S-7-methoxysyringylglycerol(9),红景天苷(10),(7S,8R)syringoylglycerol (11),丁香醛(12),2,6-二甲氧基-1,4-苯醌(13),正丁基-β-D-吡喃果糖苷(14)和焦谷氨酸正丁酯(15)。结论 化合物1~11,14~15为首次从鲜竹沥中分离得到,化合物14和15为提取过程中产生的β-D-吡喃果糖苷和焦谷氨酸人工产物。

Abstract

OBJECTIVE To study the chemical constituents of bamboo juice. METHODS The compounds were isolated and purified by column chromatography on silica gel, ODS, macroporous resin, MPLC and HPLC. Their structures were elucidated by NMR spectroscopic evidence and compared with those in literature. RESULTS Fifteen compounds were isolated and identified as (+)-lyoniresinol-3α-O-β-D-glucopyranoside (1), 5,5'-dimethoxylariciresinol-4'-O-β-D-glucopyranoside (2), syringaresinol 4'-O-β-D-glucopyroside (3), (-)-4-epi-lyoniresinol (4), (-)-lyoniresinol -2α-O-β-D-glucopyranoside (5), (+)-lyoniresinol (6), 8,8'-bisdihydrosiringenin glucoside (7), 2,4,6-trimethoxyphenyl-1-O-β-D-glucopyranoside (8), threo-8S-7-meth-oxysyringylglycerol (9), salidroside (10), (7S,8R)syringoylglycerol (11), syringaldehyde (12), 2,6-dimethoxy-1,4-benzoquinone (13), n-butyl-β-D-fructopyranoside (14), and n-butyl pyroglutamate (15).CONCLUSION Compounds 1-11 and 14-15 are isolated from bamboo juice for the first time. Compounds 14 and 15 are β-D-fructopyranoside and pyroglutamic acid artifacts produced during the extraction.

关键词

鲜竹沥 / 化学成分 / 木脂素 / (+)-南烛木树脂酚-3α-O-β-D-吡喃葡萄糖苷

Key words

bamboo juice / chemical constituents / lignans / (+)-lyoniresinol-3α-O-β-D-glu-copyranoside

引用本文

导出引用
林凯鹏, 付辉政, 周志强, 姚金龙, 赵青群, 罗跃华. 鲜竹沥正丁醇部位的化学成分研究[J]. 中国药学杂志, 2020, 55(16): 1325-1330 https://doi.org/10.11669/cpj.2020.16.002
LIN Kai-peng, FU Hui-zheng, ZHOU Zhi-qiang, YAO Jin-long, ZHAO Qing-qun, LUO Yue-hua. N-Butanol-Soluble Chemical Constituents from Bamboo Juice[J]. Chinese Pharmaceutical Journal, 2020, 55(16): 1325-1330 https://doi.org/10.11669/cpj.2020.16.002
中图分类号: R284   

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基金

江西省重点研发计划项目资助(20171BBG70103);国家药典委员会药品标准提高项目资助
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